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The phyloDE package fits linear model on inter-species gene expression data, combining Phylogenetic Comparative Methods implemented in phylolm with moderated statistics tailored for gene expression implemented in limma.

With a design matrix that expresses a grouping conditions at the tip of a phylogeny, phyloDE can perform Differential Expression analysis.

The main function of the package is phylolmFit, that inherits from the interfaces of both phylolm and limma.

See also

Author

Paul Bastide, Mélina Gallopin, Arnaud Liehrmann